[1]汪小平,王向红,等.亚精胺对诱导DNA凝聚行为的影响研究[J].温州大学学报(自然科学版),2013,(02):024-28.
 WANG Xiaoping,WANG Xianghong,The Effects of Spermidine on DNA Condensation Behavior[J].Journal of Wenzhou University,2013,(02):024-28.
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亚精胺对诱导DNA凝聚行为的影响研究
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《温州大学学报》(自然科学版)[ISSN:1674-3563/CN:33-1344/N]

卷:
期数:
2013年02期
页码:
024-28
栏目:
物理与电子科学
出版日期:
2013-05-25

文章信息/Info

Title:
The Effects of Spermidine on DNA Condensation Behavior
作者:
汪小平1王向红12?
1.温州大学物理与电子信息工程学院学院,浙江温州 325035;
2.温州职业技术学院,浙江温州 325035
Author(s):
WANG Xiaoping1 WANG Xianghong12
1. School of Physics and Electronic Information, Wenzhou University, Wenzhou, China 325035;
2. Wenzhou Vocational & Technical College, Wenzhou, China 325035
关键词:
AFM亚精胺DNA凝聚加入次数培养时间
Keywords:
AFM Spermidine DNA Condensation Adding Times Culture Time
分类号:
Q-336
文献标志码:
A
摘要:
利用原子力显微镜技术(AFM)研究了亚精胺加入次数及不同培养时间对DNA凝聚行为的影响.研究表明,DNA的凝聚行为取决于亚精胺的加入次数和培养时间.随着加入次数的增加,DNA凝聚减慢、凝聚体尺寸变大;随着培养时间的增加,DNA凝聚体变得越来越紧凑.本研究可为DNA凝聚行为的药理特性和生物学效应提供科学依据.
Abstract:
By using atomic force microscopy (AFM), we systematically studied the effects of spermidine-adding times and culture time on DNA condensation. The research showed that: DNA condensation strongly depends on the spermidine-adding times and culture time. With the adding times increasing, DNA condensates slowly, and DNA condensation becomes bigger; with culture time increasing, DNA condensates fast, and DNA condensation becomes more and more compact. The conclusions of this study can provide the scientific basis for the pharmacological characteristics and biological effects of DNA condensation behavior.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2013-01-09
基金项目:国家自然科学基金(20774066,20974081,21174131,21104060);国家自然科学基金重点项目(20934-04)
作者简介:汪小平(1988- ),女,江西吉安人,硕士研究生,研究方向:高分子物理.? 通讯作者,wangxh@wzu.edu.cn
更新日期/Last Update: 2013-05-25